Book The Best Hotels in Santa Cruz Tlaxcala for 2026 from CA $49 - Fully Refundable Options

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Our top choices for Santa Cruz Tlaxcala hotels

A corridor with stone walls, wooden beams, and potted plants.

An interior with stone arches, a reception desk, and wooden flooring.

A courtyard with stone walls, a street lamp, and outdoor seating.

A restaurant with wooden tables and chairs, a bar area, and a black wall with 'MEXKO' branding.

1. Centro Vacacional La Trinidad

Santa Cruz Tlaxcala

marelis

CA $55

CA $66 total

includes taxes & fees

Oct 14 - Oct 15

A cozy lounge area with a wooden ceiling, blue walls, and a chandelier. There are blue chairs and a brown sofa.

A dining area with tables, chairs, and a high ceiling with wooden beams.

An indoor venue with tables set for a formal event, a pool area, and a DJ booth.

A grand hall with a large Christmas tree decorated with ornaments and lights, a geometric stained glass ceiling, and a staircase with railings.

2. Hotel San Francisco Tlaxcala

Tlaxcala

Luis Daniel

CA $102

CA $120 total

includes taxes & fees

Oct 5 - Oct 6

A spacious lobby with blue sofas, a reception desk, and a second-floor balcony.

A hotel room with a kitchenette, a blue sofa, a bed with a blue and white bedspread, a wooden desk, and a view of trees through the window.

A hotel room with a bed, desk, chair, and a window with a view.

3. City Express by Marriott Apizaco

Apizaco

Martin

CA $117

CA $137 total

includes taxes & fees

Oct 11 - Oct 12

A stone building with a large wooden door and a covered entrance.

A buffet with various food items including fruits, vegetables, and different types of bread.

A spacious lobby with high ceilings, exposed brick arches, and a mix of seating areas including a leather couch and a wooden table.

An indoor swimming pool with a wooden ceiling and stone walls.

4. Holiday Inn Tlaxcala by IHG

Yauhquemehcan

Ian

CA $151

CA $178 total

includes taxes & fees

Oct 31 - Nov 1

A breakfast table with plates of food, drinks, and a vase of flowers.

A hallway with a stone wall at the end, a hanging light fixture, and potted plants.

A reception area with a dark reception desk, two blue sofas with patterned cushions, a coffee table with a vase of red flowers, and a wall with a geometric design.

5. Hotel Mirante Tlaxcala

Tlaxcala

Agustin S

CA $77

CA $91 total

includes taxes & fees

Oct 5 - Oct 6

A courtyard with a fountain, potted plants, and a bench.

A stone building entrance with a sign reading "POSADA ACASONA DE CORTES".

A Christmas tree decorated with colorful lights and ornaments in a lobby area with a polished floor and a staircase.

6. Hotel Posada La Casona de Cortes

Tlaxcala

Atilio

CA $55

CA $65 total

includes taxes & fees

Oct 11 - Oct 12

A restaurant with outdoor seating, a view of the city, and a mural on the wall.

A building with vibrant murals, a reception area, and a well-maintained garden.

A spacious room with a high ceiling, large windows, and a round table with chairs.

A hotel room with two wooden beds, a desk, a chair, a television, and a window with a view.

7. Hotel de La Loma

Tlaxcala

Mario

CA $58

CA $68 total

includes taxes & fees

Oct 18 - Oct 19

An indoor swimming pool with a glass ceiling, tiled floor, and a mural wall.

A restaurant with multiple tables and chairs, a large TV screen, and a view of greenery outside.

A restaurant with outdoor seating, wooden tables, and chairs, a large TV screen, and a banner with text.

A bar area with three cocktails on the counter, a glass with a lemon slice, and a variety of liquor bottles in the background.

8. Hotel Senorial Tlaxcala

Tlaxcala

Maria

CA $104

CA $122 total

includes taxes & fees

Oct 21 - Oct 22

A restaurant with outdoor seating, covered by a wooden roof, and surrounded by palm trees.

A hotel lobby with a reception desk, a staircase, and a check-in counter.

A building with a brick facade, large windows, and potted plants.

A spacious indoor dining area with high ceilings, wooden beams, and large windows. Tables are arranged for dining, and there are chairs and tables set up for guests.

9. HOTEL XIADANI temazcal y SPA

Tlaxcala

Danae

CA $47

CA $55 total

includes taxes & fees

Oct 4 - Oct 5

A covered outdoor seating area with tiled flooring, metal-framed chairs, and a view of a cityscape.

A modern kitchen with a flat-screen TV, wooden furniture, and a patterned backsplash.

A modern living area with a grey sofa, a wooden reception desk, and a clock on the wall.

A building facade with three hotel signs: HOTEL BOUTIQUE, LAS TORRES, and a partially visible third sign.

10. Capital O Hotel Boutique Las Torres

Tlaxcala

CLEMENTE

CA $62

CA $78 total

includes taxes & fees

Oct 28 - Oct 29

A courtyard with a fountain, well-kept hedges, and a building with multiple balconies and arched windows.

A reception area with a brick wall, wooden counter, and hanging pendant lights.

A courtyard with a fountain, a covered carriage, and a building with a tiled roof.

A swimming pool with blue chairs and a covered area with a glass ceiling.

11. Hotel del Angel, Apizaco

San Martin de Porres

CA $110

CA $130 total

includes taxes & fees

Oct 15 - Oct 16

A hotel room with two beds, a brick wall, a stained glass window, and a round mirror on the wall.

A building with a balcony, brick walls, and windows with lights.

A modern bathroom with two toilets, a wooden bench, and a large window with curtains.

A narrow corridor with wooden beams, potted plants, and a metal railing.

12. Hotel de la Capilla

Tlaxcala

Diana

CA $62

CA $74 total

includes taxes & fees

Oct 7 - Oct 8

A hotel room with a bed, a bedside table, a lamp, a TV, and a window with a view of palm trees.

A reception desk with a wooden counter and black base, a black office chair, and a glass door leading to a hallway.

A hotel hallway with a framed poster, a decorative vase, and a bench.

A restaurant with multiple wooden tables and chairs, a tiled floor, and a modern interior design.

13. Hotel Tlaxcala

Tlaxcala

Angelica

CA $65

CA $76 total

includes taxes & fees

Oct 7 - Oct 8

A modern house with a glass door entrance, a well-maintained garden, and a concrete pathway leading to the door.

A hotel room with a large bed, a bedside table with a phone, a small bedside table with a tissue box, and a wall-mounted artwork above the bed.

A modern outdoor area with a concrete pathway, a small lawn, and various plants including a palm tree.

A modern hallway with a staircase leading to a balcony, two sofas, and a small table.

14. Casa Tlaxcalli by Beddo Hoteles

Tlaxcala

Thomas

CA $68

CA $80 total

includes taxes & fees

Oct 5 - Oct 6

A building with a sign reading "Le Posse de".

A banquet hall with round tables, white tablecloths, and chairs with pink sashes.

A hotel room with a bed, a desk, a chair, a TV, a bathroom with a bathtub, and a staircase.

A building with a covered outdoor seating area, a metal railing, and planters with grass.

15. Hotel La Posada

Apizaco

Eduardo

CA $79

CA $93 total

includes taxes & fees

Oct 5 - Oct 6

A modern hotel with a glass facade, multiple floors, and a prominent signage for 'Encore'.

A modern indoor recreational area with pool tables, foosball, and bar seating.

A modern indoor pool with clear glass walls, a metal ladder, and a view of a cityscape at night.

A modern interior with a glass staircase, a reception desk, and a unique ceiling light fixture.

16. Ramada Encore by Wyndham Puebla

Coronango

Marisol

CA $107

CA $127 total

includes taxes & fees

Nov 2 - Nov 3

A swimming pool with a glass bottom, surrounded by lounge chairs and a potted plant.

A horse statue in front of a building with a cross and a clock.

A restaurant with brick arches, wooden tables, and chairs.

A building with a brick facade, large glass doors, and a sign that reads "HOPCORN."

17. Hotel Cuamanco

Huamantla

Doug

CA $42

CA $50 total

includes taxes & fees

Oct 4 - Oct 5

A modern cafeteria with white and red tables and chairs, large windows, and a kitchen area.

A hotel room with two beds, a desk, and a window with a view of a building and trees.

A hotel with a modern orange facade, multiple windows, and a sign reading "cityexpress junior."

A clean reception area with two computer stations, white chairs, and a view of the street through a large window.

18. City Express Junior by Marriott Puebla Finsa

Cuautlancingo

Ewa

CA $77

CA $92 total

includes taxes & fees

Oct 16 - Oct 17

A room with two beds, each with green and white bedding, a stone-patterned wall, and a brick fireplace.

A modern bathroom with a toilet, sink, and shower.

A hotel room with two beds, a small desk, and a window with curtains.

A bathroom with a sink, toilet, and shower.

19. Sendero de San Francisco

Apizaco

"La atención de Rosana la dueña y toda su familia fue excelente , súper atenta a nuestras necesidades . Nosotros llegamos a las 11 pm y nos recibieron muy bien la habitación tibia a pesar del clima que es un poco frío. Agua caliente . Todo limpio y tipo cabaña , en la mañana nos ofrecieron café y pan . La recomiendo al 100% si es que van a realizar actividades cercanas a la zona es una excelente opción . Nosotros fuimos a Huamantla y a las minas de Tiza ."

ILIANA

CA $48

CA $57 total

includes taxes & fees

Oct 5 - Oct 6

A stone archway leading to a white building with a wooden door, surrounded by a gravel path and a small grassy area.

A diner with checkered flooring, red booths, and chrome bar stools.

A gym with various exercise equipment, including a squat rack and weight benches.

A bathroom with a large bathtub, a white chair, and a green wall.

20. Hotel Azucena

Huamantla

Micaela

CA $56

CA $66 total

includes taxes & fees

Nov 2 - Nov 3

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Top Santa Cruz Tlaxcala Hotel Reviews

Fiesta Inn Parque Puebla

10/10 Excellent

"Friendly staff ,super clean , always helpful"

City Express by Marriott Apizaco

10/10 Excellent

"We arrived after a long stretch of driving and we were pulling a trailer. The staff went out of their way to assist us in parking the trailer in a secured area in their parkade and also walked us down the street to a restaurant to ensure it was still open and food would be available. Way above and beyond service!"

NH Puebla Finsa

10/10 Excellent

"Nice place and convenient"

La Bella Toscana Centro

10/10 Excellent

"It was a beautiful room, it had a fridge with free drinks and coffee and the people was very nice and kind."

Plaza Poblana

10/10 Excellent

"The hotel is conveniently located by the bus station. The property is very well maintained. The room has everything you need and the bed was very comfortable. I loved the decor inside the hotel in the hallways. I would definitely stay here again."

Hotel Royal Puebla

10/10 Excellent

"Todo muy limpio, las camas muy cómodas y un excelente servicio."

Pietro Santo

10/10 Excellent

"Excellent service"

More cheap stays in Santa Cruz Tlaxcala

Hotel Kapu Puebla

Boulevard Norte 4228-19 Puebla PUE

CA $41

CA $49 total

Oct 23 - Oct 24

includes taxes & fees

8/10 Very good! (100 reviews)

Hotel Royal Puebla

Atilac San Felipe Hueyotlipan Puebla PUE

CA $44

CA $53 total

Oct 7 - Oct 8

includes taxes & fees

Casa Tlaxcalli by Beddo Hoteles

Av. 20 de Noviembre Tlaxcala TLAX

CA $68

CA $80 total

Oct 5 - Oct 6

includes taxes & fees

9/10 Wonderful! (64 reviews)

Hotel Finca Belen

1 Belén Sexta Sección Tlaxco TLAX

CA $83

CA $98 total

Oct 4 - Oct 5

includes taxes & fees

6/10 (1 review)

Pietro Santo

Sta Isa Tetlahuaca Km2 San Miguel Xoxtla Santeagueda TLAX

CA $100

CA $119 total

Oct 4 - Oct 5

includes taxes & fees

9.4/10 Exceptional! (174 reviews)

La Bella Toscana Centro

Fundadores #92, Val'Quirico Santeagueda TLAX

CA $142

CA $168 total

Oct 4 - Oct 5

includes taxes & fees

9.8/10 Exceptional! (158 reviews)

Frequently asked questions

Where is the best place for a stay in Santa Cruz Tlaxcala?

Centro Vacacional La Trinidad is one of the top choices for your stay based on our traveler data. This hotel offers 3 outdoor pools and 2 restaurants. Two other choices for your stay in the area are Fiesta Inn Parque Puebla and Marriott Puebla Hotel Meson del Angel. See all available top hotels, or vacation rentals in Santa Cruz Tlaxcala.

What are some of the best vacation home rentals that Santa Cruz Tlaxcala has to offer?

Luxurious Casa Residencial Privada: This highly rated vacation home rental in Santa Cruz Tlaxcala offers a balcony and laundry facilities to help you feel comfortable in your new surroundings. Kitchen amenities like a microwave and kitchenware can make your vacation run smoothly. See all vacation rentals in Santa Cruz Tlaxcala.

If I need to cancel my hotel reservation in Santa Cruz Tlaxcala, will I receive a refund?

Yes, you'll find most hotel reservations are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz Tlaxcala.

How is it to stay in Santa Cruz Tlaxcala?

Visitors can enjoy all that Santa Cruz Tlaxcala has to offer including its parks. In Santa Cruz Tlaxcala, there are 2 hotels and other accommodations to choose from. Find out more about Santa Cruz Tlaxcala.

What should I see while I'm in Santa Cruz Tlaxcala?

Places to visit in the wider area include Basilica of Ocotlan, Xicotencatl Theater, and Xicotencatl National Park. You'll also find La Malinche National Park and Cacaxtla in the area. Check out what more to see and do in Expedia's Santa Cruz Tlaxcala guide.

What's the weather like in Santa Cruz Tlaxcala?

The hottest months are usually April and May with an average temp of 61°F, while the coldest months are January and December with an average of 54°F. The rainiest months in Santa Cruz Tlaxcala are August, September, July, and June, with each month seeing an average of 10 inches of rainfall.

Find hotels in Santa Cruz Tlaxcala from CA $49

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Santa Cruz Tlaxcala

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Santa Cruz Tlaxcala hotels

1. Centro Vacacional La Trinidad

2. Hotel San Francisco Tlaxcala

3. City Express by Marriott Apizaco

4. Holiday Inn Tlaxcala by IHG

5. Hotel Mirante Tlaxcala

6. Hotel Posada La Casona de Cortes

7. Hotel de La Loma

8. Hotel Senorial Tlaxcala

9. HOTEL XIADANI temazcal y SPA

10. Capital O Hotel Boutique Las Torres

11. Hotel del Angel, Apizaco

12. Hotel de la Capilla

13. Hotel Tlaxcala

14. Casa Tlaxcalli by Beddo Hoteles

15. Hotel La Posada

16. Ramada Encore by Wyndham Puebla

17. Hotel Cuamanco

18. City Express Junior by Marriott Puebla Finsa

19. Sendero de San Francisco

20. Hotel Azucena

Top Santa Cruz Tlaxcala Hotel Reviews

Fiesta Inn Parque Puebla

City Express by Marriott Apizaco

NH Puebla Finsa

La Bella Toscana Centro

Plaza Poblana

Hotel Royal Puebla

Pietro Santo

More cheap stays in Santa Cruz Tlaxcala

Hotel Kapu Puebla

Hotel Royal Puebla

Casa Tlaxcalli by Beddo Hoteles

Hotel Finca Belen

Pietro Santo

La Bella Toscana Centro

Frequently asked questions

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